eClinical Technology and Industy News

Ambys Medicines Presents New Data Further Validating its Novel Liver Cell Replacement Therapy Platform at the ASGCT Annual Meetin

Data on Genetically Engineered Hypoimmunogenic Human Hepatocytes Demonstrate Proof of Concept in a Metabolic Liver Disease Model

Excerpt from the Press Release:

SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)–Ambys Medicines, a company pioneering cell-replacement therapies for patients with liver disease, today announced new data on its universal hepatocyte program in an oral presentation at the American Society of Gene and Cell Therapy 25th Annual Meeting at 3:45 p.m. ET. This presentation accompanies two scientific posters presented earlier in the week on the company’s platform technology and cutting-edge hyperfunctional hepatocyte program. Combined, these data demonstrate Ambys’s potential to generate high-quality, functional human hepatocytes and further engineer hepatocytes to treat a broad range of diseases.

Ambys’s proprietary platform enables the first and only development and manufacture of functional human hepatocytes, unlocking the full potential of hepatocyte replacement therapy. Liver disease is a massively underserved problem in healthcare, leading to irreversible outcomes for most patients and more than two million deaths globally each year.

“Our new data show that Ambys is capable at efficient genetic modification of primary human hepatocytes, unleashing a powerful combination of cell and gene therapy in hepatocytes,” said Ron Park, M.D., Chief Executive Officer of Ambys Medicines. “The universal hepatocyte data presented today coupled with the data on our hyperfunctional human hepatocyte program and in vivo bioreactor platform presented earlier this week further validate our breakthrough replacement cell therapy approach for severe liver diseases. We continue to make great progress building our pipeline of enhanced hepatocytes with the goal of bringing hepatocyte cell replacement to patients with liver failure and genetic liver diseases.”

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