Veracyte Announces New Study Published in Cell Shows that Decipher Prostate Test Predicts Chemotherapy Benefit in Patients with Metastatic Prostate Cancer

Findings are from the multicenter, prospective, Phase 3 STAMPEDE trial

Excerpt from the Press Release:

SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)–Veracyte, Inc. (Nasdaq: VCYT), a leading genomic diagnostics company, and University College London (UCL) today announced that data published online in Cell show that the Decipher Prostate Genomic Classifier predicts which patients with metastatic cancer are likely to benefit from treatment intensification with the chemotherapy docetaxel and which are not likely to benefit and can therefore avoid unnecessary toxicity. The findings—from the randomized, prospective, Phase 3 STAMPEDE trial—are the first to be published showing that a gene expression test can help clinicians better personalize chemotherapy decisions for patients with metastatic prostate cancer.

Globally, nearly 1.5 million new cases of prostate cancer are diagnosed each year and the disease accounts for a fifth (nearly 400,000) of all cancer-related deaths in men, with these numbers expected to increase over the next two decades.^1,2 In the United States, nearly 315,000 patients will be diagnosed with prostate cancer this year and it is the second-leading cause of cancer deaths among men.³ Most prostate cancer deaths occur in patients who first presented with advanced or metastatic disease—a group that has been growing faster in recent years in the U.S., compared to those presenting with localized disease.³

“Our findings suggest that the Decipher Prostate test may provide an important new tool to help guide treatment decisions for the growing population of patients with metastatic prostate cancer,” said Professor Gerhardt Attard, director of UCL Cancer Institute and STAMPEDE trial co-investigator.

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