eClinical Technology and Industy News

Freenome Presents Data Demonstrating the Importance of Clinical Test Performance and Screening Adherence on Colorectal Cancer Outcomes

Excerpt from the Press Release:

SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)–Freenome, the privately held biotechnology company that has pioneered a comprehensive multiomics platform for early cancer detection using a routine blood draw, today announced results from two different studies using “CRC – Microsimulation of Adenoma Progression and Screening”, or CRC-MAPS™, a novel semi-Markov microsimulation model of the adenoma-carcinoma pathway.

The first study revealed that changes in adenoma sensitivity have a greater impact on CRC incidence and mortality reduction than changes in either CRC sensitivity or specificity. This study suggests that earlier detection of colorectal neoplasia improves clinical outcomes and highlights the benefits of preventing CRC through adenoma detection and subsequent lifelong colonoscopy surveillance.

The second study emphasized the importance of screening test adherence and the time that elapses between screening tests (test interval) on clinical outcomes. This study indicated that imperfect adherence mimics delays in screening, with both resulting in worse outcomes. These results reinforce the critical role of adherence in reducing CRC incidence and mortality, and suggest that the availability of a blood test with improved patient adherence may significantly improve clinical outcomes.

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