eClinical Technology and Industy News

Javelin Biotech Aims to Develop Industry-Leading “Organ-on-a-Chip” Predictive Pharmacokinetics Platform in Collaboration with Pfizer Inc.

Excerpt from the Press Release:

WOBURN, Mass.–(BUSINESS WIRE)–Javelin Biotech (“Javelin”) today announces a three-year collaboration with Pfizer Inc. (NYSE: PFE) to design and build what could potentially be an industry-leading platform to evaluate ADME (absorption, distribution, metabolism and excretion) properties of small molecules. The ADME platform will integrate a microphysiological system (MPS), commonly referred to as “organ-on-a-chip,” with interactive computational software to help inform human pharmacokinetic (PK) predictions, a key measure in evaluating new drug candidates in preclinical research. If successful, Javelin plans to commercialize the platform for broad industry adoption; it would potentially be the first “organ-on-a-chip” system on the market specifically designed for human PK predictions.

Under terms of the agreement, the companies will bring together Javelin’s in-depth tissue engineering and microfluidics expertise and Pfizer’s leading expertise in human PK predictions to create the ADME platform. Javelin will design, build and test the platform, and Pfizer will provide industry guidance for real-world usage, as well as drug and data sets to help validate the platform’s predictions. Javelin will retain any potential commercialization rights to the platform. Financial details were not disclosed.

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