Synthace and Ipsen Partner to Accelerate Novel Therapeutic Development Through Automation
Excerpt from the Press Release:
BOSTON & LONDON–(BUSINESS WIRE)–Synthace Ltd and Ipsen, a global biopharmaceutical company focused on innovation and specialty care, have partnered to accelerate development of novel biotherapeutics targeting multiple therapeutic areas, including oncology, endocrinology, pain management, regenerative medicine and rare diseases. Ipsen has automated design and construction of therapeutic candidates using Synthace’s integrative software platform, Antha. The process aims to speed up biotherapeutic candidate entry into the screening pipeline and shorten development time for treatment of diseases via targeted secretion inhibition.
Ipsen has developed novel biotherapeutic molecules, called Targeted Secretion Inhibitors (TSIs). TSIs are a fusion of select parts of the botulinum neurotoxin with another protein domain to redirect its mode of action, resulting in a unique targeted therapeutic. The design and construction of TSIs is both labour intensive and manually complex, typically taking 30 days to develop between 24-48 constructs which then go on to therapeutic screening.
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