Twist Bioscience Signs Antibody Discovery Collaboration with MediSix Therapeutics to Develop T-cell Therapies
Excerpt from the Press Release:
OUTH SAN FRANCISCO–(BUSINESS WIRE)–Twist Bioscience Corporation (NASDAQ: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, and MediSix Therapeutics, a cell therapy company creating novel therapeutics to target T-cell leukemia and lymphoma, today announced a collaboration to discover novel antibodies against five undisclosed targets.
Under the terms of the collaboration, Twist will leverage its proprietary Library of Libraries to discover five novel antibodies directed against MediSix’s targets. MediSix will use its unique platform technologies to develop novel CAR T-cell therapies targeting malignancies and autoimmune diseases without any CAR T-cell fractricide. Twist will receive an upfront payment and will be eligible to receive success-based clinical and regulatory milestone payments, as well as royalties on product sales.
“We believe Twist’s exceptional antibody discovery and optimization platform and extensive libraries, coupled with the company’s ability to move quickly and efficiently, will support our efforts to develop effective immune cell therapies that specifically modulate relevant molecules and combat T-cell malignancies and autoimmune diseases,” said Andrew Bruce, CEO of MediSix Therapeutics. “We look forward to continued work with Twist as we build our pipeline.”
“We look forward to collaborating with MediSix to overcome existing challenges of using cell therapy approaches to treat T-cell malignancies, often because of a lack of antigen targets specific to the cancer. Pairing MediSix’s novel targets with our ability to discover and optimize antibodies to efficiently target these devastating cancers has the potential to add an important and needed therapeutic option for patients,” said Emily M. Leproust, Ph.D., CEO and co-founder of Twist Bioscience. “In addition, with MediSix’s locations in Boston, U.S. and Singapore, this agreement deepens our global footprint and presence in the Asia Pacific region, where certain types of T-cell cancers are more prevalent.”
About MediSix Therapeutics Pte. Ltd.
Renowned expert in cell therapy and the creator of the first anti-CD19 CAR, Professor Dario Campana founded MediSix Therapeutics in 2016 to help patients with B-cell malignancies. Since then, MediSix Therapeutics has developed and leveraged on several unique groundbreaking proprietary technologies to build a pipeline of research products with the aim of overcoming the major challenges in the treatment of cancer and autoimmune diseases.
Click the button below to read the entire Press Release:
Discover What Sets TrialStat Apart From Ordinary EDC Platforms
Click the image or button below to explore our eClinical Suite Platform and discover what sets TrialStat apart from competing EDC platforms.
Request Your Demo Today!
From rapid database build through database lock, we deliver consistent quality on-time and on-budget. Ready to upgrade your eClinical toolkit?