UBC researchers say they’ve found ‘weak spot’ in all COVID-19 variants that could lead to better treatment
Scientists say certain antibody fragment effectively neutralized variants by latching to vulnerability
Excerpt from the Press Release:
Researchers at the University of British Columbia (UBC) have discovered what they describe as a “weak spot” in all of the major variants of the virus that causes COVID-19 — a revelation they believe could open the door for treatments to fight current and future mutations.
In a peer-reviewed study published Thursday, the research team said they found a largely consistent soft spot — like a dent in the virus’s spike protein armour — that has survived the coronavirus’s mutations to date. Scientists determined a certain antibody fragment was able to “effectively neutralize” all the variants, to some degree, because it exploited the vulnerability.
“What’s exciting is what it tells us we can do now. Once you know the [weak] spot, it’s a bit like the gold rush analogy. We know where to go,” said Sriram Subramaniam, the study’s senior author and a professor with UBC’s faculty of medicine.
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