FibroGen Announces Completion of Patient Enrollment in MATTERHORN, a Phase 3 Clinical Study of Roxadustat for the Treatment of Anemia in Patients with Lower Risk Transfusion-Dependent Myelodysplastic Syndromes (MDS)

– 141 MDS Patients Enrolled –
– Topline Data Anticipated 1H:2023 –

Excerpt from the Press Release:

SAN FRANCISCO, Aug. 26, 2022 (GLOBE NEWSWIRE) — FibroGen, Inc. (NASDAQ: FGEN) today announced completion of patient enrollment for MATTERHORN, a Phase 3 clinical study of roxadustat for treatment of anemia in patients with lower risk transfusion-dependent myelodysplastic syndromes (MDS).

“We are very pleased to complete enrollment of this Phase 3 study of roxadustat for the treatment of anemia in patients with lower risk MDS,” said Mark Eisner, M.D, M.P.H, Chief Medical Officer, FibroGen. “Patients living with MDS have limited treatment options for their anemia, and MATTERHORN evaluates roxadustat as a potential new treatment that can reduce the burden of blood transfusions. On behalf of the entire study team, we would like to extend our gratitude to the patients, caregivers, investigators, and study staff for their commitment to this study.”

A total of one-hundred forty-one (141) subjects have been enrolled in MATTERHORN, a Phase 3, double-blind placebo-controlled study investigating the efficacy and safety of roxadustat for treatment of anemia in patients with lower risk transfusion-dependent myelodysplastic syndromes. The primary endpoint of the study is transfusion independence for ≥ 56 consecutive days in the first 28 weeks of treatment. The main secondary endpoint is reduction of red blood cell transfusion. Top-line data from the MATTERHORN study is anticipated in 1H 2023. For more information about MATTERHORN please visit www.clinicaltrials.gov (NCT03263091).

Click the button below to read the entire Press Release:

Continue Reading The Press Release