TumorGen and PhenoVista Capture the Seeds that Drive Cancer Metastasis
TumorGen’s microfluidic platform traps metastatic cancer cell clusters from lung cancer patients, creating new opportunities for anti-metastatic drug development.
Excerpt from the Press Release:
SAN DIEGO–(BUSINESS WIRE)–TumorGen Inc., and PhenoVista Biosciences LLC have successfully isolated and characterized metastatic cancer cell clusters (MCCCs) from the blood of lung cancer patients’, validating TumorGen’s novel MCCC capture technology. This achievement is a critical milestone in developing anti-metastatic drugs, called “cluster busters,” which will target these cells and prevent cancer metastasis.
“Anti-metastatic therapies that can stop tumors from forming in other organs is a tremendous unmet medical need,” said TumorGen Founder / President, Jeffrey K. Allen, Ph.D. “Our platform can identify where MCCCs are vulnerable so researchers can develop drugs targeting these deadly clusters. TumorGen will partner with oncology drug development companies to bring these new therapies to the clinic.”
Metastasis causes around 90% of cancer deaths. While scientists have long known that MCCCs drive metastasis, no one has efficiently collected them from patient blood. This study, supported by the National Cancer Institute shows that MCCCs can be readily captured, allowing for genomic and other analyses to identify their vulnerabilities and enable new therapies.
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