Exo Therapeutics Presents Key Data at FOCIS 2024 Demonstrating the Efficacy of Potent and Selective Exosite-targeted TBK1/STING Inhibitor in Multiple Preclinical Models

– Oral and poster presentations show novel, differentiated properties optimized to progress company’s nomination of lead development candidate for the treatment of autoimmune diseases –

– FOCIS recognizes Exo with 2024 Annual Meeting Award for exceptional research and posters of merit –

Excerpt from the Press Release:

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Exo Therapeutics, Inc., a company developing a pipeline of drug candidates that target exosites, unique small-molecule binding pockets that are distal to traditional active and allosteric sites, thereby reprogramming enzyme activity for precise and robust therapeutic effect, today presented a poster and oral presentation on its preclinical program targeting TBK1/STING interaction of the cGAS-STING pathway at the 24th Annual Meeting of the Federation of Clinical Immunology Societies (FOCIS 2024) in San Francisco.

Data presented in both the poster and oral presentation show that the company has identified potent, selective exosite-targeted TBK1/STING inhibitors, demonstrated efficacy across preclinical models and optimized properties towards development candidate nomination. FOCIS also recognized Exo with the 2024 Annual Meeting Award for exceptional research and posters of merit for the Company’s poster and oral presentation.

“Exo’s data look very promising, particularly the targeting of both interferon-beta and NF-kB pathways by your molecule,” said Mary K. Crow, M.D., Physician-in-Chief Emeritus at Hospital for Special Surgery and Professor of Medicine at Weill Cornell Medical College.

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