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IgGenix Demonstrates Potential of IGNX001 as a Targeted Therapeutic for Peanut Allergy at the 2024 EAACI Annual Meeting Ahead of Clinical Trial Launch

Additional data presented showcased the expansive potential of the SEQ SIFTER™ platform in the discovery and characterization of IgE antibodies in Atopic Dermatitis

Excerpt from the Press Release:

SOUTH SAN FRANCISCO, Calif., June 3, 2024 /PRNewswire/ — IgGenix, Inc., a preclinical antibody discovery and development company taking a revolutionary approach to address IgE-mediated diseases, presented data on the company’s lead candidate, IGNX001, an IgG4 monoclonal antibody-based therapeutic candidate for peanut allergy. The company also presented data in Atopic Dermatitis (AD), showcasing the widespread utility of its proprietary SEQ SIFTER™ antibody discovery platform in IgE-mediated disease beyond allergies. These data were presented during the 2024 European Academy of Allergy and Clinical Immunology (EAACI) Annual Meeting, which took place in Valencia, Spain on May 31 – June 3, 2024.

Highlights from EAACI:

  • Peanut-specific therapeutic candidate, IGNX001, demonstrated potent inhibition of peanut-mediated mast cell degranulation, providing a case study of how this assay could serve as a valuable pharmacodynamic marker in clinical trials.
  • IgGenix’s proprietary SEQ SIFTER platform enables discovery of IgE antibodies involved in atopic diseases including AD.

“At IgGenix, we’re developing revolutionary treatments for peanut and other severe allergies. These therapeutics are designed to offer an appealing alternative for allergic patients that want protection against allergen exposure in a matter of days instead of months,” said Derek Croote, Ph.D., Chief Technical Officer of IgGenix. “Our pioneering SEQ SIFTER discovery platform is also unlocking IgE biology in an unprecedented way and we are excited to be working with our fantastic European collaborators on this new direction.”

IgGenix will be launching its first human clinical trial in peanut allergy later this year.

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