Aethlon Medical Announces Publication of Preclinical Data Showing Ability of the Hemopurifier® to Remove Extracellular Vesicles and microRNAs from Renal Perfusates Following Controlled Oxygenated Rewarming of Discarded Donor Kidneys
Results Support Future Study of the Hemopurifier® as Part of a Machine Perfusion Circuit to Further Assess its Association with Function of Retrieved Kidneys
Excerpt from the Press Release:
SAN DIEGO, Aug. 27, 2024 /PRNewswire/ — Aethlon Medical, Inc. (Nasdaq: AEMD), a medical therapeutic company focused on developing products to treat cancer and life-threatening infectious diseases, today announced the publication in preprint of an in vitro study in bioRxiv on August 24, 2024, entitled, “The Hemopurifier® Removes Extracellular Vesicles and microRNAs From Renal Perfusates Following Controlled Oxygenated Rewarming of Discarded Donor Kidneys.”
Aethlon Medical’s Hemopurifier® is a therapeutic blood filtration system designed to bind and remove harmful exosomes and life-threatening viruses from blood and other biological fluids, qualities which have potential applications in oncology and infectious diseases, as well as in the organ transplant setting.
“Kidney transplantation provides the highest quality of life for those afflicted with end stage renal disease, yet a significant shortage in the number of donor kidneys currently exists,” stated Steven LaRosa, MD, Senior Author of the paper and Chief Medical Officer of Aethlon Medical. “To bridge the gap between recipients and donors, the criteria for the use of kidneys from deceased brain death and diseased circulatory death donors has been extended. However, kidneys from extended criteria donors are associated with higher rates of poor graft function and acute rejection in recipients. The release of extracellular vesicles (EVs) and microRNAs from the donor kidney are hypothesized to play a role in these complications and are targets for the, Hemopurifier®.”
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