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Evofem Biosciences Addresses the Impact of GLP-1 Medications on Oral Contraceptive Absorption and Introduces Phexxi as a Non-Oral Solution

Excerpt from the Press Release:

SAN DIEGO, Aug. 20, 2024 /PRNewswire/ — As the popularity of GLP-1 receptor agonists continues to surge in the treatment of obesity and type 2 diabetes, Evofem Biosciences, Inc. (OTCQB: EVFM) is raising awareness of the potential impact these medications may have on the effectiveness of oral contraceptives. With an increasing number of women turning to GLP-1 medications for weight management and glycemic control, the need for reliable non-oral contraceptive options has never been more acute.

GLP-1 receptor agonists, including well-known medications such as semaglutide and tirzepatide, are celebrated for their ability to aid in weight loss and improve blood sugar levels. However, these medications are also associated with gastrointestinal side effects, including nausea, vomiting, and delayed gastric emptying, which can interfere with the absorption of oral contraceptives. This reduced absorption can make oral birth control less effective, increasing the risk of unintended pregnancies.

Evofem Biosciences is proud to offer Phexxi® (lactic acid, citric acid and potassium bitartrate), a hormone-free, on-demand contraceptive gel that provides women with a reliable non-oral birth control option. Phexxi is uniquely suited for patients who are prescribed GLP-1 medications and are concerned about the potential for reduced effectiveness of oral contraceptives due to drug-drug interaction.

“The rise in GLP-1 usage brings important considerations for women’s reproductive health,” said Saundra Pelletier, CEO of Evofem Biosciences. “Understanding the impact of these medications on oral contraceptive absorption and effectiveness is critical. Phexxi offers a non-oral alternative that allows women to manage their contraception without worrying about compromised absorption.”

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