COVID-19

SARS-CoV-2 Infection Prevented and Treated in Human Lung Tissue Model

02/13/2021

Excerpt from the Article: Given the steady numbers of new COVID-19 cases, the appearance of new variants, and the considerable time that vaccinations will take to reach target levels needed for herd immunity, the development of treatments and useful therapeutics remains a top priority. In particular, treatments and preventive approaches that can be widely and…

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UHN-led study shows antiviral drug speeds up clearance of COVID-19

02/12/2021

Excerpt from the Article: A clinical study led by Dr. Jordan Feld, a liver specialist at UHN’s Toronto Centre for Liver Disease, showed an experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients – patients who do not need to be hospitalized. This could become an important intervention to treat infected patients and…

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Experimental stem cell therapy a potential weapon against COVID-19

02/12/2021

Excerpt from the Article: When the COVID-19 pandemic hit, researchers in Canada and around the world moved quickly to pivot their research and help with the development of new treatments and vaccines.  At The Ottawa Hospital, this resulted in more than 60 different research projects and trials, including an innovative clinical trial of mesenchymal stem…

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Vaxart Announces Positive Preliminary Data from Phase 1 Clinical Trial Evaluating Its Oral COVID-19 Tablet Vaccine Candidate

02/12/2021

Excerpt from the Press Release: SOUTH SAN FRANCISCO, Calif., Feb. 03, 2021 (GLOBE NEWSWIRE) — Vaxart, Inc., (NASDAQ: VXRT), a clinical-stage biotechnology company developing oral vaccines administered by tablet, today announced preliminary data from its Phase 1 study of VXA-CoV2-1 showing that its oral COVID-19 tablet vaccine candidate was generally well-tolerated, and immunogenic as measured by…

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NeuroRx Initiates Phase 2/3 Study of Inhaled ZYESAMI™ for Severe COVID-19 with UCI Health

02/11/2021

Excerpt from the Press Release: RADNOR, Pa. and IRVINE, Calif., Feb. 3, 2021 /PRNewswire/ — NeuroRx, Inc. today announced initiation of a Phase 2/3 clinical trial investigating the role of inhaled ZYESAMI™ (aviptadil) for the treatment of patients with Severe COVID-19 in partnership with UCI Health of the University of California, Irvine. UCI Health was…

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Atea Pharmaceuticals Announces First Patient Dosed in Phase 2 Virology Trial of AT-527 in Outpatient Setting

02/10/2021

Excerpt from the Press Release: BOSTON, Feb. 04, 2021 (GLOBE NEWSWIRE) — Atea Pharmaceuticals, Inc. (Nasdaq: AVIR) (“Atea”), a clinical-stage biopharmaceutical company, today announced that the first patient has been dosed in the Phase 2 virology trial evaluating AT-527 in mild or moderate COVID-19 patients in an outpatient setting. The trial will enroll patients in…

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Corvus Pharmaceuticals Initiates Phase 3 Clinical Trial of CPI-006 for Patients with COVID-19

02/09/2021

Excerpt from the Press Release: BURLINGAME, Calif., Feb. 04, 2021 (GLOBE NEWSWIRE) — Corvus Pharmaceuticals, Inc. (NASDAQ: CRVS), a clinical-stage biopharmaceutical company, today announced that it has initiated a Phase 3 clinical trial of CPI-006 for the treatment of hospitalized patients with COVID-19. The study is expected to enroll approximately 1,000 patients at sites in…

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Humanigen Completes Enrollment in Phase 3 Study of Lenzilumab in Hospitalized Patients with COVID-19

02/01/2021

Excerpt from the Press Release: BURLINGAME, Calif.–(BUSINESS WIRE)–Humanigen, Inc. (NASDAQ:HGEN) (“Humanigen”), a clinical stage biopharmaceutical company focused on preventing and treating an immune hyper-response called cytokine storm with its lead drug candidate lenzilumab™, today announced it has completed enrollment for its pivotal phase 3 study of lenzilumab for COVID-19. The Company expects to announce top-line…

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Cepheid Receives Health Canada License for SARS-CoV-2, Flu A, Flu B and RSV Combination Test

01/30/2021

Excerpt from the Press Release: “The ability to run a single, highly-sensitive test that detects SARS-CoV-2, Flu A, Flu B, and respiratory syncytial virus provides actionable results and helps to alleviate pressure on the healthcare system,” said Dr. David Persing, MD, Ph.D., Chief Medical and Technology Officer at Cepheid. “Xpert® Xpress SARS-CoV-2/Flu/RSV delivers reference lab quality testing in…

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fMRI Identifies Smell and Taste Malfunction in COVID-19 Patients

01/29/2021

Excerpt from the Article: Images captured with fMRI in a case study reveal the role of the orbitofrontal cortex in patients infected with the virus who experience anosmia and ageusia. Functional MRI (fMRI) has helped increase understanding about the loss of smell and taste that frequently accompany COVID-19 infection. The answer lies in the orbitofrontal…

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