eClinical Technology and Industy News

Carmot Therapeutics Launches Spin-Off, Kimia Therapeutics, to Focus on Metabolic Disease

– Spin-off of technology platform to newly-formed Kimia Therapeutics intended to maximize the full potential of Carmot’s metabolic portfolio while enabling Kimia to pursue a broad range of opportunities across oncology, immunology and inflammation –

– Encouraging clinical data from CT-388 and CT-868, Carmot’s dual GLP-1/GIP receptor modulators, represent significant opportunity for Carmot to advance the treatment of obesity and its many co-morbidities –

– Heather Turner, JD, to become CEO of Carmot; Stig K. Hansen, PhD, to become CEO of Kimia –

Excerpt from the Press Release:

BERKELEY, Calif., Jan. 05, 2023 (GLOBE NEWSWIRE) — Carmot Therapeutics, Inc. (Carmot), a clinical-stage biotechnology company developing disease-modifying therapies for metabolic diseases, today announced its intent to spin off its Chemotype Evolution (CE) discovery platform in the fields of oncology, immunology and inflammation, to a separate and new company, Kimia Therapeutics (Kimia). Carmot will focus on metabolic disease by advancing its proprietary portfolio of clinical and preclinical therapeutics modulating gut hormones and related energy homeostasis mechanisms, while preserving exclusive access to the CE discovery platform for metabolic disease through a partnership with Kimia.

Carmot’s co-founder and current Chief Executive Officer (CEO), Stig K. Hansen, PhD, will become CEO of Kimia. Heather Turner, JD, Carmot’s current Chief Operating Officer, has been appointed CEO of Carmot. Ms. Turner has over 20 years of leadership experience in life science companies including senior operational roles and legal expertise.

The spin-off enables Carmot to focus on clinical-stage candidates CT-388 and CT-868 (dual GLP-1/GIP receptor modulators), additional Investigational New Drug (IND)-stage programs including CT-996 (an oral, small molecule GLP-1 receptor agonist) and a long-acting peptide tyrosine-tyrosine (PYY) analogue. Both CT-388 and CT-868 have recently demonstrated clinically meaningful data in obese adults with or without type 2 diabetes.

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