eClinical Technology and Industy News

New Duke University-led Study Shows That Vaxart’s Oral COVID-19 Vaccine Candidate Reduces Airborne Transmission of SARS-CoV-2 Infection in Animal Model

Data published in bioRxiv confirmed previous findings suggesting mucosal vaccines could reduce transmission of airborne viruses such as COVID-19 and flu more than injectable vaccines
Study suggests mucosal vaccines may protect not only vaccinated, but also unvaccinated animals

Excerpt from the Press Release:

SOUTH SAN FRANCISCO, Calif., Oct. 7, 2021 /PRNewswire/ — A Duke University-led study published in bioRxiv showed that Vaxart, Inc.’s (NASDAQ: VXRT) investigational oral tablet vaccine reduced the airborne transmission of SARS-CoV-2 virus in an animal model.

These results are consistent with those from Vaxart’s Phase II human flu challenge study, which showed that Vaxart’s oral tablet vaccine was better at reducing shedding than the injectable flu vaccine comparator.

A limitation of the currently approved injected COVID-19 vaccines is that airborne transmission occurs in people who have received them. The preclinical study also demonstrated that Vaxart’s oral vaccine platform induces robust systemic and mucosal responses.

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